Citric Acid+potassium Citrate
About Citric Acid+potassium Citrate
Citric Acid+potassium Citrate is an oral medication used to make your urine less acidic. It is primarily prescribed to prevent the formation of certain kidney stones, such as calcium oxalate, uric acid, and cystine stones, and to manage metabolic acidosis. By raising the pH of your urine, it helps dissolve existing crystals and prevents new stones from developing.
For the best results, you must take Citric Acid+potassium Citrate regularly and consistently exactly as your doctor instructs. This liquid medication is typically taken after meals or within 30 minutes of bedtime to prevent stomach irritation, and it must always be diluted in water or juice. Drinking plenty of fluids and lowering your salt intake can significantly improve your treatment outcomes.
Some people using Citric Acid+potassium Citrate may experience mild side effects like a temporary upset stomach, mild diarrhoea, or nausea. However, you should contact your doctor immediately if you develop serious symptoms such as severe abdominal pain, muscle weakness, or a slow, irregular heartbeat.
Before starting this medicine, talk to your doctor if you have kidney disease, heart problems, or high potassium levels. Do not take this if you have severe kidney failure, untreated Addison's disease, or if you are severely dehydrated, as it can cause dangerous shifts in your electrolyte levels.
This medicine can interact with other treatments, particularly blood pressure drugs like ACE inhibitors, potassium-sparing water pills, and antacids. If you are pregnant, breastfeeding, or are an older adult, you should consult your doctor or pharmacist to make sure this product is safe for you.
Uses of Citric Acid+potassium Citrate
Medicinal Benefits
Citric Acid+potassium Citrate helps reduce the risk of kidney stone formation and supports relief from discomfort caused by urinary tract acidity.
The following are the benefits of Citric Acid+potassium Citrate:
- Helps reduce the risk of kidney stone formation.
- Reduces burning and discomfort during urination.
- Improves urinary comfort by balancing acidity levels.
- Supports long-term kidney health and function.
- Helps prevent the growth and recurrence of urinary crystals.
- Promotes better overall urinary tract comfort and well-being.
Directions for Use
- Measure your dose carefully using the calibrated measuring cup or spoon provided with the medicine. Do not use a regular household spoon.
- Mix the measured dose thoroughly with a full glass (about 8 ounces) of water or cold fruit juice.
- Drink the entire mixture slowly. Taking it after meals can help prevent stomach upset.
- Drink extra water throughout the day to help your kidneys flush out crystals.
- Never take this medication undiluted. Always follow your doctor's exact instructions regarding how much to take and when to take it.
Storage
Side Effects of Citric Acid+potassium Citrate
Common Side Effects (Usually mild):
- Nausea or vomiting
- Mild stomach pain or cramping
- Loose stools or mild diarrhoea
- Mild gas or bloating
Serious Side Effects (Call a doctor right away):
- Signs of high potassium levels (such as muscle weakness, tingling in hands or feet, or a slow, irregular heartbeat)
- Severe stomach pain or black, tarry stools
- Confusion, dizziness, or extreme tiredness
- Signs of a severe allergic reaction (such as skin rash, itching, hives, or swelling of the face, lips, and throat)
Medicines Containing this Salt
View AllDrug Warnings
- Dilute before drinking: Always mix this medicine with water before taking it. Drinking it without diluting can irritate your throat and stomach.
- Check the liquid before use: Make sure the liquid is clear and free of particles. Do not use it if it looks cloudy, has changed colour, or contains floating particles.
- Measure the dose correctly: Always use the measuring cup, spoon, or syringe provided with the medicine. This helps you take the correct dose every time.
- Attend regular check-ups: Keep all scheduled blood and urine tests. These help your doctor check your potassium and acid levels and make sure your treatment remains safe.
- Inform your healthcare provider: Tell your doctor, surgeon, or dentist that you are taking this medicine before any medical or dental procedure.
Drug Interactions
- Blood pressure medications (e.g., spironolactone, enalapril, lisinopril): Taking these blood pressure medications with Citric Acid+potassium Citrate can lead to dangerously high potassium levels in your blood.
- Aluminium-containing antacids (e.g., aluminium hydroxide, magaldrate): Taking these antacids alongside Citric Acid+potassium Citrate can increase aluminium absorption, which can be harmful, especially if you have kidney problems.
- Nonsteroidal anti-inflammatory drugs (e.g., aspirin, salsalate): Citric Acid+potassium Citrate can increase how quickly your body eliminates these medications, potentially reducing their effectiveness.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAlcohol consumption may worsen your health condition.
Pregnancy
cautionCitric Acid+potassium Citrate is a pregnancy category C drug. It should not be taken until prescribed. Your doctor will weigh the benefits and potential risks before prescribing them. Please consult your doctor.
Breast Feeding
cautionThere is limited data on how Citric Acid+potassium Citrate affects breastfeeding. Please consult your doctor before taking Citric Acid+potassium Citrate. Your doctor will weigh the benefits and potential risks before prescribing them.
Driving
safe if prescribedCitric Acid+potassium Citrate may not affect your ability to drive.
Liver
safe if prescribedCitric Acid+potassium Citrate can be used in patients with liver diseases if prescribed.
Kidney
cautionCitric Acid+potassium Citrate should be used with caution in patients with kidney diseases. Dose adjustments may be necessary.
Children
cautionThe safety and effectiveness of Citric Acid+potassium Citrate in children have not been established. Please consult your doctor before giving Citric Acid+potassium Citrate to children.
Habit Forming
Diet & Lifestyle Advise
- Drink plenty of fluids: Aim to drink at least 2 to 3 litres of water daily (unless your doctor advises otherwise) to keep your urine diluted and help prevent stone formation.
- Reduce your salt intake: High sodium levels can increase the amount of calcium in your urine, raising the risk of kidney stones. Limit processed foods, canned soups, and table salt.
- Limit foods high in oxalates: If you are prone to calcium oxalate stones, try to limit dietary oxalates found in foods like spinach, rhubarb, nuts, and chocolate.
- Eat moderate protein: Consuming too much animal protein (like red meat, poultry, and shellfish) can increase uric acid levels and make your urine more acidic.
- Incorporate citrus fruits: Consuming lemons, limes, and oranges can naturally boost citrate levels in your urine, helping Citric Acid+potassium Citrate work more effectively.
Special Advise
- Following a specific diet plan created by your nutritionist to control your health condition is essential.
- Your doctor may advise you to take blood and urine tests while using Citric Acid+potassium Citrate to examine your health condition and ensure that this medicine treats your condition.
Patients Concern
Disease/Condition Glossary
Gout: Gout is a type of arthritis in which patients experience severe pain, redness, and swelling in joints. The most common affected area is the joint at the base of the big toe. Patients with gout may often experience acute attacks that result in sudden and severe pain. It occurs due to a condition called hyperuricemia (high uric acid levels in the body). The excess uric acid deposit and crystallize in the joints leading to pain and inflammation.
Kidney stones: It is a condition in which hard deposits occur in the kidney leading to stones. A kidney stone comprises mainly four types of calcium oxalate, uric acid, struvite, and cystine. It is due to the increased level of uric acid in the body. As a result, uric acid crystals start depositing in the kidney, known as renal calculi/nephrolithiasis/urolithiasis.
Metabolic acidosis: Metabolic acidosis is a condition in which excess acid is accumulated in the body due to the kidney's inability to remove excess acid from the body. It can be of various types, such as lactic acidosis (build-up of lactic acid), diabetic acidosis (build-up of ketone bodies), and hyperchloremic acidosis (build-up of sodium bicarbonate). It is mostly seen in patients with kidney impairment.
FAQs
Citric Acid+potassium Citrate is used to reduce the acidity of the urine. This function aids in the kidneys elimination of uric acid, which helps prevent kidney stones and gout. Additionally, this medicine can be used to prevent and treat kidney disease-related metabolic issues such as diabetic ketoacidosis.
Citric Acid+potassium Citrate combines two medicines: Citric acid and Potassium citrate. Citric acid and Potassium citrate are alkaline in nature and work by neutralizing the blood and urine acids.
Citric Acid+potassium Citrate should not be used along with antacids as it may cause electrolyte imbalances. So, before taking Citric Acid+potassium Citrate, inform your doctor about all the prescription or non-prescription medicines you are taking.
You should closely monitor your regular blood tests and electrocardiograms to ensure safety, renal function, and electrolytes. Besides this, frequent checks of potassium levels are required for kidney impairments.
Citric Acid+potassium Citrate should be taken as long as your doctor prescribes it for you. Consult your doctor before stopping any medicine, don't stop your medication suddenly.
Do not take diuretics like triamterene, spironolactone, or amiloride while you are taking Citric Acid+potassium Citrate unless your doctor says it to take. Together Citric Acid+potassium Citrate and potassium-sparing diuretics' rise in serum potassium concentration may produce cardiac arrest. Also, do not take food containing high levels of potassium, such as almonds, apricots, bananas, beans (lima, pinto, white), cantaloupe, carrot juice (canned), figs, grapefruit juice, halibut, milk, oat bran, potato (with skin), salmon, spinach, tuna, etc.
The common side effects of Citric Acid+potassium Citrate include diarrhoea, stomach upset, nausea, and vomiting. If any of these side effects persist or worsen, please inform your doctor.
No, do not consume alcohol with Citric Acid+potassium Citrate, as alcohol may interfere with its effectiveness or worsen your health condition.
Citric Acid+potassium Citrate consists of two medications, including citric acid and potassium citrate, which help reduce the acidity of the urine.
Citric Acid+potassium Citrate comes as an oral liquid. Take it exactly as your doctor has prescribed. Be sure to shake the bottle well before each use. Use the provided measuring cup, and take the prescribed dose by mouth.
You are advised to take Citric Acid+potassium Citrate for as long as your doctor has prescribed it, depending on your medical condition.
Citric Acid+potassium Citrate should not be taken by individuals who are allergic to any of its components. It should also be avoided by people with hyperkalaemia (high potassium levels), as it may increase potassium levels in the body.
Citric Acid+potassium Citrate should be used during pregnancy only if your doctor prescribes it. Your doctor will assess the potential benefits and risks before recommending Citric Acid+potassium Citrate.
Yes, you should avoid taking potassium supplements, salt substitutes, or low-salt dietary products while taking Citric Acid+potassium Citrate unless advised otherwise by the doctor.
Before starting treatment with Citric Acid+potassium Citrate, inform your doctor about any allergies or existing medical conditions, such as hyperkalaemia (high potassium levels), dehydration (fluid loss), heat cramps, adynamia episodica hereditaria (a condition causing periods of muscle weakness), kidney disease, heart disease, difficulty urinating, untreated Addison's disease (a disorder where the adrenal glands produce insufficient hormones), high blood pressure during pregnancy, oedema (swelling), and chronic diarrhoea.
Consult the doctor before taking Citric Acid+potassium Citrate with other medicines, particularly antacids containing aluminium (aluminium hydroxide, aluminium carbonate), pain relievers (aspirin), antipsychotic medications (lithium), medications used to treat urinary tract infections (methenamine, nitrofurantoin), medications used to treat arrhythmia (quinidine), potassium-sparing diuretics (triamterene, spironolactone, amiloride), antihistamines (diphenhydramine, brompheniramine), antihypertensives (enalapril, captopril, fosinopril), antidepressants (amitriptyline, amoxapine, desipramine, doxepin, imipramine), and medications used to treat overactive bladder (solifenacin, darifenacin).
Diluting Citric Acid+potassium Citrate in water or juice is essential because the concentrated solution can severely irritate your mouth, oesophagus, and stomach. Dilution makes it much gentler on your digestive tract. Talk to your doctor if you experience persistent stomach discomfort.
It is highly recommended to take Citric Acid+potassium Citrate after meals or within 30 minutes of bedtime. Taking it with food or on a full stomach helps prevent stomach upset and diarrhoea. Talk to your doctor or pharmacist if you have trouble scheduling your doses.
No, you should avoid salt substitutes containing potassium. Combining them with Citric Acid+potassium Citrate can cause potassium levels in your blood to rise to unsafe levels. Talk to your doctor before making major dietary changes.
Signs of high potassium include muscle weakness, numbness or tingling in your hands or feet, confusion, and a slow or irregular heartbeat. If you experience any of these symptoms, seek immediate medical attention and talk to your doctor.
Regular tests are necessary to check your urine pH and monitor the electrolyte levels (like potassium) in your blood. This helps your doctor adjust your dose to ensure the medication is both safe and effective. Talk to your doctor for more details about your monitoring schedule.
Yes, Citric Acid+potassium Citrate can help dissolve certain types of existing stones, such as uric acid stones, by making the urine less acidic. However, it may not dissolve all types of kidney stones. Talk to your doctor about the specific type of stones you have.

